Asymmetric predominantly ipsilateral blepharospasm and contralateral parkinsonism in an elderly patient with a right mesencephalic cyst

作者: Carlos Singer , Norman J. Schatz , Brian Bowen , David Eidelberg , Ken Kazumata

DOI: 10.1002/MDS.870130125

关键词: Central nervous system diseaseMagnetic resonance imaging of the brainPathologyParkinsonismCystBlepharospasmResting tremorLesionDystoniaPsychology

摘要: A 66-year-old woman presented with a 3-year history of predominantly right-sided blepharospasm and 1-year progressive left-sided hemiparkinsonism manifested by left upper extremity resting tremor bradykinesia. Magnetic resonance imaging the brain revealed large right mesencephalic cyst mass effect. Positron emission tomography bilateral striatal hypometabolism consistent nigrostriatal dopaminergic dysfunction. The association ipsilateral contralateral is very rare, its posterior fossa space-occupying lesion has been reported only once. This second report such an first description adult-onset symptomatology.

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