Germline BRCA2 mutations in men with breast cancer.
作者： E Mavraki , IC Gray , DT Bishop , NK Spurr
DOI: 10.1038/BJC.1997.574
关键词: Mutation 、 Cancer research 、 Male breast cancer 、 BRCA2 Protein 、 Germline mutation 、 Mammary gland 、 Breast cancer 、 Biology 、 Missense mutation 、 Germline
摘要: Breast cancer in men is rare and clearly due some cases to an inherited predisposition. A total of 28 male breast patients were tested for BRCA2 mutations; two frameshifts one putative missense mutation identified. One the was detected same position as a estimated be responsible 40% all Iceland.
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