Advances in nanotechnology-based carrier systems for targeted delivery of bioactive drug molecules with special emphasis on immunotherapy in drug resistant tuberculosis – a critical review

摘要: From the early sixteenth and seventeenth centuries to present day of life, tuberculosis (TB) still is a global health threat with some new emergence resistance. This type poses vital challenge control TB cases across world. Mortality morbidity rates are high due this face TB. The newer nanotechnology-based drug-delivery approaches involving micro-metric nano-metric carriers much needed at stage. These delivery systems would provide more advantages over conventional treatment by producing enhanced therapeutic efficacy, uniform distribution drug molecule target site, sustained controlled release molecules lesser side effects. main aim develop these novel improve patient compliance reduce therapy time. article reviews elaborates concepts for solid-lipid particulate (solid-lipid micro- nanoparticles, nanostructured lipid carriers), vesicular (liposomes, niosomes liposphere), emulsion-based (micro nanoemulsion) other effective role immunomodulators as an adjuvant management MDR-TB XDR-TB.