Baicalein exhibits anti-inflammatory effects via inhibition of NF-κB transactivation.

作者: Raghavendra S. Patwardhan , Deepak Sharma , Maikho Thoh , Rahul Checker , Santosh K. Sandur

DOI: 10.1016/J.BCP.2016.03.013

关键词: ThioredoxinThioredoxin reductaseNF-κBCytokine secretionT cellBaicaleinCell biologyTransactivationPharmacologyTranscription factorChemistry

摘要: … of NF-κB but did not suppress Concanavalin A induced NF-κB. Since baicalein did not inhibit NF-κB binding to DNA, we hypothesized that baicalein may be suppressing NF-κB trans-…

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