作者: A. Lefébure , E. Papy , C. Rioux , S. Diamantis , L. Armand-Lefèvre
DOI: 10.1016/J.MEDMAL.2015.04.008
关键词: Carbapenem 、 Medical prescription 、 Antibiotic use 、 Context (language use) 、 Significant difference 、 Psychological intervention 、 Intensive care medicine 、 Epidemiology 、 Audit 、 Medicine
摘要: Abstract Objective The emergence of extended-spectrum beta-lactamase (ESBL) producing Enterobacteriaceae has resulted in the increase carbapenem prescriptions. objective our study was to determine appropriateness prescriptions from initiation reassessment treatment, between 2009 and 2011. Patients method A questionnaire drafted by infectious diseases specialists (IDS) microbiologists used collect clinical microbiological data concerning An IDS then compared results assess prescription compliance with hospital's local recommendations. Results Seventy-one were included 32 treatment had been most frequently probabilistic treat nosocomial infections. revealed that number multidrug-resistant (MDR) infections increased 2011, especially involving ESBL-producing . At reassessment, 15 (21%) 12 (38%) appropriate continued. Overall, when comparing 2 periods, complied guidelines without any statistically significant difference (68% 75% 2011). Conclusion Our showed MDR due ; this consistent epidemiological data. We also proved compliant mobile interventions medical surgical departments helped reach rate compliance. Carbapenem stewardship may be promoted even a difficult context, for duration or at reassessment.