Desmoplastic infantile ganglioglioma--clinicopathological and immunohistochemical study of four cases.
作者： Pritilata Rout , Vani Santosh , Anita Mahadevan , Sastry V. Kolluri , T. Yasha
DOI: 10.1007/S00381-002-0610-3
关键词: Neuroepithelial cell 、 Neural stem cell 、 Pathology 、 Biology 、 Ganglioglioma 、 Desmoplastic infantile ganglioglioma 、 Central nervous system disease 、 Immunohistochemistry 、 P53 protein 、 Dig
摘要: Abstract Case reports. Four cases of desmoplastic infantile ganglioglioma (DIG) seen in India are described. These patients presented with large, supratentorial, superficially situated cystic tumours that showed glial and ganglionic differentiation; accompanied by a severe reaction. MIB-1 labelling was rare, despite foci apparently primitive neuroepithelial cells. There lacking p53 protein expression tumour cells all cases. The prognosis good following either partial or complete resection. DIGs distinct form developmental tumour, probably arising from neural progenitor subcortical zone along mature subpial astrocytes. Conclusions. In view its favourable prognosis, this has to be diagnosed accurately immunohistochemical techniques using neuronal markers. absence suggests DIG different molecular genetic pathways other supratentorial astrocytomas.
springer.com
sci-hub.se 参考文章(23)
Lucien Jules Rubinstein, Dorothy S. Russell, Pathology of tumours of the nervous system ,(1977)
Scott R. VandenBerg, Estelle E. May, Lucien J. Rubinstein, Mary M. Herman, E. Perentes, S. A. Vinores, V. Peter Collins, T. S. Park, Desmoplastic supratentorial neuroepithelial tumors of infancy with divergent differentiation potential ("desmoplastic infantile gangliogliomas"). Report on 11 cases of a distinctive embryonal tumor with favorable prognosis. Journal of Neurosurgery. ,vol. 66, pp. 58- 71 ,(1987) , 10.3171/JNS.1987.66.1.0058
Patricia K. Duffner, Peter C. Burger, Michael E. Cohen, Robert A. Sanford, Jeffrey P. Krischer, Roy Elterman, Patricia A. Aronin, Jeanette Pullen, Marc E. Horowitz, Andrew Parent, Paul Martin, Larry E. Kun, Desmoplastic infantile gangliogliomas: An approach to therapy Neurosurgery. ,vol. 34, pp. 583- 589 ,(1994) , 10.1227/00006123-199404000-00003
A Serra, J Strain, S Ruyle, Desmoplastic cerebral astrocytoma of infancy: report and review of the imaging characteristics. American Journal of Roentgenology. ,vol. 166, pp. 1459- 1461 ,(1996) , 10.2214/AJR.166.6.8633464
G. Tamburrini, C. Colosimo, F. Giangaspero, R. Riccardi, C. Di Rocco, Desmoplastic infantile ganglioglioma Childs Nervous System. ,vol. 19, pp. 292- 297 ,(2003) , 10.1007/S00381-003-0743-Z
David N. Louis, Andreas von Deimling, G. Richard Dickersin, Elizabeth C. Dooling, Bernd R. Seizinger, Desmoplastic cerebral astrocytomas of infancy: a histopathologic, immunohistochemical, ultrastructural, and molecular genetic study. Human Pathology. ,vol. 23, pp. 1402- 1409 ,(1992) , 10.1016/0046-8177(92)90061-7
Mark F. Mehler, Renato Rozental, Maryjane Dougherty, David C. Spray, John A. Kessler, Cytokine regulation of neuronal differentiation of hippocampal progenitor cells Nature. ,vol. 362, pp. 62- 65 ,(1993) , 10.1038/362062A0
Jean-Pierre de Chadarévian, Jogi V. Pattisapu, Eric N. Faerber, Desmoplastic cerebral astrocytoma of infancy: Light microscopy, immunocytochemistry, and ultrastructure Cancer. ,vol. 66, pp. 173- 179 ,(1990) , 10.1002/1097-0142(19900701)66:1<173::AID-CNCR2820660131>3.0.CO;2-H
Patricia J. Renfranz, Miles G. Cunningham, Ronald D.G. McKay, Region-specific differentiation of the hippocampal stem cell line HiB5 upon implantation into the developing mammalian brain Cell. ,vol. 66, pp. 713- 729 ,(1991) , 10.1016/0092-8674(91)90116-G
O. R. Tenreiro-Picon, S. V. Kamath, J. R. Knorr, R. L. Ragland, T. W. Smith, K. Y. Lau, Desmoplastic infantile ganglioglioma: CT and MRI features Pediatric Radiology. ,vol. 25, pp. 540- 543 ,(1995) , 10.1007/BF02015789