Biomarker Development Study Publication Standards are Dead—Long Live Biomarker Development Study Publication Standards!

作者: James Lyons-Weiler

DOI: 10.4137/CIN.S0

关键词: Evidence-based practicePredictive modellingBiomarker (medicine)MEDLINEFeature selectionComparative evaluationData scienceInformaticsMedicineHealth informatics

摘要: At the University of Pittsburgh, I teach a graduate-level course ‘The Practical Analysis High-Throughput Genomic and Proteomic Data’. 50% grade is based on paper project re-analysis published data sets. The aim to encourage comparative evaluation different approaches various analytic tasks for – omic biomarker studies. students are empowered by this understand see themselves that normalization, feature selection, disease prediction model (a) exist, (b) differ in their apparent relative performance helping generate lists therapeutic targets or models. We also learn about standards, mostly from perspective formats, which critical algorithm

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