CRISPR-Cas9: A Revolutionary Tool for Cancer Modelling
作者： Raul Torres-Ruiz , Sandra Rodriguez-Perales
关键词: Genome engineering 、 In patient 、 CRISPR 、 Process (engineering) 、 Biology 、 Genetics 、 Gene mutation 、 Genome 、 Cancer 、 Genome editing 、 Computational biology
摘要: … The CRISPR-Cas9 system for genome editing has been proven as a robust technology that … at low cost. In this review, we will discuss the innovative applications of the CRISPR-Cas9 …
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Corina E. Antal, Andrew M. Hudson, Emily Kang, Ciro Zanca, Christopher Wirth, Natalie L. Stephenson, Eleanor W. Trotter, Lisa L. Gallegos, Crispin Miller, Frank Furnari, Tony Hunter, John Brognard, Alexandra C. Newton, Abstract 125: Protein kinase C loss-of-function mutations in cancer reveal role as tumor suppressor Cancer Research. ,vol. 75, pp. 125- 125 ,(2015) , 10.1158/1538-7445.AM2015-125
Vivek Iyer, Bin Shen, Wensheng Zhang, Alex Hodgkins, Thomas Keane, Xingxu Huang, William C Skarnes, None, Off-target mutations are rare in Cas9-modified mice. Nature Methods. ,vol. 12, pp. 479- 479 ,(2015) , 10.1038/NMETH.3408
Masakazu Hashimoto, Tatsuya Takemoto, Electroporation enables the efficient mRNA delivery into the mouse zygotes and facilitates CRISPR/Cas9-based genome editing. Scientific Reports. ,vol. 5, pp. 11315- 11315 ,(2015) , 10.1038/SREP11315
Nadia P Castro, Natalie D Fedorova-Abrams, Anand S Merchant, Maria Cristina Rangel, Tadahiro Nagaoka, Hideaki Karasawa, Malgorzata Klauzinska, Stephen M Hewitt, Kajal Biswas, Shyam K Sharan, David S Salomon, None, Cripto-1 as a novel therapeutic target for triple negative breast cancer Oncotarget. ,vol. 6, pp. 11910- 11929 ,(2015) , 10.18632/ONCOTARGET.4182
Alfred G. Knudson, Two genetic hits (more or less) to cancer Nature Reviews Cancer. ,vol. 1, pp. 157- 162 ,(2001) , 10.1038/35101031
Masahiro Sato, Miyu Koriyama, Satoshi Watanabe, Masato Ohtsuka, Takayuki Sakurai, Emi Inada, Issei Saitoh, Shingo Nakamura, Kazuchika Miyoshi, Direct Injection of CRISPR/Cas9-Related mRNA into Cytoplasm of Parthenogenetically Activated Porcine Oocytes Causes Frequent Mosaicism for Indel Mutations. International Journal of Molecular Sciences. ,vol. 16, pp. 17838- 17856 ,(2015) , 10.3390/IJMS160817838
Meghna Das Thakur, Nancy K Pryer, Mallika Singh, Mouse tumour models to guide drug development and identify resistance mechanisms The Journal of Pathology. ,vol. 232, pp. 103- 111 ,(2014) , 10.1002/PATH.4285
Dietmar W. Hutmacher, Raymund E. Horch, Daniela Loessner, Simone Rizzi, Shirly Sieh, Johannes C. Reichert, Judith A. Clements, Justus P. Beier, Andreas Arkudas, Oliver Bleiziffer, Ulrich Kneser, Translating tissue engineering technology platforms into cancer research Journal of Cellular and Molecular Medicine. ,vol. 13, pp. 1417- 1427 ,(2009) , 10.1111/J.1582-4934.2009.00853.X
Randall J. Platt, Sidi Chen, Yang Zhou, Michael J. Yim, Lukasz Swiech, Hannah R. Kempton, James E. Dahlman, Oren Parnas, Thomas M. Eisenhaure, Marko Jovanovic, Daniel B. Graham, Siddharth Jhunjhunwala, Matthias Heidenreich, Ramnik J. Xavier, Robert Langer, Daniel G. Anderson, Nir Hacohen, Aviv Regev, Guoping Feng, Phillip A. Sharp, Feng Zhang, CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling Cell. ,vol. 159, pp. 440- 455 ,(2014) , 10.1016/J.CELL.2014.09.014
Danilo Maddalo, Eusebio Manchado, Carla P. Concepcion, Ciro Bonetti, Joana A. Vidigal, Yoon-Chi Han, Paul Ogrodowski, Alessandra Crippa, Natasha Rekhtman, Elisa de Stanchina, Scott W. Lowe, Andrea Ventura, In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system Nature. ,vol. 516, pp. 423- 427 ,(2014) , 10.1038/NATURE13902