Significance and Applications of Murine Models in Cancer Research: Guidelines for Selecting the Best Model

Shurtleff Sa, Raimondi Sc, Hancock Ml, Pui Ch, Rubnitz Je, Behm Fg, Grosveld G, Downing, Chan Gc, Buijs A, TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis. Leukemia. ,vol. 9, pp. 1985- 1989 ,(1995)

Vernon E. Steele, Ronald A. Lubet, Richard C. Moon, Preclinical Animal Models for the Development of Cancer Chemoprevention Drugs Humana Press. pp. 39- 46 ,(2005) , 10.1007/978-1-59259-768-0_2

Jeanette Woiterski, Martin Ebinger, Kai E. Witte, Barbara Goecke, Vanessa Heininger, Martin Philippek, Michael Bonin, Andre Schrauder, Silja Röttgers, Wolfgang Herr, Peter Lang, Rupert Handgretinger, Udo F. Hartwig, Maya C. André, Engraftment of low numbers of pediatric acute lymphoid and myeloid leukemias into NOD/SCID/IL2Rcγnull mice reflects individual leukemogenecity and highly correlates with clinical outcome International Journal of Cancer. ,vol. 133, pp. 1547- 1556 ,(2013) , 10.1002/IJC.28170

NV Giridharan, Mouse as a model organism - From animals to cells Indian Journal of Medical Research. ,vol. 136, pp. 683- ,(2012)

Annapoorni Rangarajan, Robert A. Weinberg, Comparative biology of mouse versus human cells: modelling human cancer in mice Nature Reviews Cancer. ,vol. 3, pp. 952- 959 ,(2003) , 10.1038/NRC1235

Frank J. Gonzalez, Ai-Ming Yu, CYTOCHROME P450 AND XENOBIOTIC RECEPTOR HUMANIZED MICE Annual Review of Pharmacology and Toxicology. ,vol. 46, pp. 41- 64 ,(2006) , 10.1146/ANNUREV.PHARMTOX.45.120403.100007

Tinneke Denayer, Thomas Stöhr, Maarten Van Roy, Animal models in translational medicine: Validation and prediction New Horizons in Translational Medicine. ,vol. 2, pp. 5- 11 ,(2014) , 10.1016/J.NHTM.2014.08.001

Melinda G Hollingshead, Luke H Stockwin, Sergio Y Alcoser, Dianne L Newton, Benjamin C Orsburn, Carrie A Bonomi, Suzanne D Borgel, Raymond Divelbiss, Kelly M Dougherty, Elizabeth J Hager, Susan L Holbeck, Gurmeet Kaur, David J Kimmel, Mark W Kunkel, Angelena Millione, Michael E Mullendore, Howard Stotler, Jerry Collins, Gene expression profiling of 49 human tumor xenografts from in vitro culture through multiple in vivo passages - strategies for data mining in support of therapeutic studies BMC Genomics. ,vol. 15, pp. 393- 393 ,(2014) , 10.1186/1471-2164-15-393

Warren E. Enker, Janet L. Jacobitz, Experimental carcinoma of the colon induced by 1,2-dimethylhydrazine-diHCI: value as a model of human disease Journal of Surgical Research. ,vol. 21, pp. 291- 299 ,(1976) , 10.1016/0022-4804(76)90040-8

Camille P. Granvil, Ai-Ming Yu, Guillermo Elizondo, Taro E. Akiyama, Connie Cheung, Lionel Feigenbaum, Kristopher W. Krausz, Frank J. Gonzalez, Expression of the Human CYP3A4 Gene in the Small Intestine of Transgenic Mice: In Vitro Metabolism and Pharmacokinetics of Midazolam Drug Metabolism and Disposition. ,vol. 31, pp. 548- 558 ,(2003) , 10.1124/DMD.31.5.548