Comparative biology of mouse versus human cells: modelling human cancer in mice
作者： Annapoorni Rangarajan , Robert A. Weinberg
DOI: 10.1038/NRC1235
关键词:
摘要: Laboratory mice have represented a powerful experimental system for understanding the intricacy of human cancer pathogenesis. Indeed, much our current conceptualization how tumorigenesis occurs in humans is strongly influenced by mouse models development. However, an emerging body evidence indicates that there are fundamental differences process and humans. What these species-specific do they affect use as tumour pathogenesis?
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