Molecular Signatures of Drug Resistance
作者： Melissa A. Troester , Jason I. Herschkowitz , Katherine A. Hoadley
DOI: 10.1007/978-0-387-89445-4_12
关键词:
摘要: Genomic methods are helping to overcome limitations of individual markers in predicting response chemotherapy. Molecular signatures cancer heterogeneity and drug resistance being developed that use data from both observational experimental settings. represent specific pathways biological processes integrated diverse types, including cell line models, genetically engineered mouse patient studies resistance. This chapter highlights recent advances future directions genomics resistance, with emphasis on integrating insights different study
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