作者: Theodore R. Sana , Glenda C. Delenstarr , Paul K. Wolber
DOI:
关键词: Artificial intelligence 、 Signal 、 Analytical chemistry 、 Nucleic acid 、 Analyte 、 Feature (computer vision) 、 Pattern recognition 、 Biology
摘要: Nucleic acid arrays that have background features, and methods for using the same, are provided. The subject nucleic include both hybridization features where provide a signal in assay is made up of feature substrate component, probe component non-specific binding component. In practicing methods, contacted with sample signals observed features. then subtracted from to obtain corrected employed as output assay, e.g., determine presence, either qualitatively or quantitatively, analyte target sample. Also provided kits use methods.