DEVELOPMENT AND VALIDATION OF UV SPECTROMETRIC METHOD FOR QUANTITATIVE DETERMINATION OF ULIPRISTAL ACETATE
作者： Apexa K Bari , Parixit R Prajapati , Sonal S Desai , Vishal S Modi
DOI:
关键词: Dosage form 、 Quantitative determination 、 Ulipristal acetate 、 Chemistry 、 Chromatography 、 Analytical chemistry 、 Routine analysis
摘要: Objective: To develop and validate UV spectrometric method for quantitative determination of ulipristal acetate. Methods: The solvent selected was methanol detection carried out at 302 nm. Results: Linearity the proposed found to be between 5–20 μg/ml. LOD LOQ were 0.0062 μg/ml 0.0187 μg/ml, respectively. % recovery 98.83 %-100.32 %. precise as values RSD obtained both intraday interday, precision studies be<2.0 robust can useful routine analysis formulations containing Conclusion: developed simple, sensitive, linear, accurate, robust. validated used acetate in bulk drugs dosage form.
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