Microneedle array chip, device and patch for transdermal drug delivery utilizing the same, and preparation method therof

摘要: The invention discloses a microneedle array chip comprising metal microneedles and substrate, wherein the consists of needle head with tip at its top, bar seat, is fixed onto substrate via seat; microneedle, having cylindrical or conical shape, inclined toward preset angle, has upper surface an oval plane ring parallel to it acute angle. in have firm structures avoid fracture, sharp tips facilitate puncturing. maximal puncturing depth easy adjust control. good uniformity, are safe reliable use. hollow microneedles, like conventional syringe needles, lateral openings, thus can effectively blockage infusion poles by skin, thereby facilitating rapid diffusion absorption drugs, resulting significant therapeutic effects.