作者: SHINSUKE MIYAZAKI , TAISHI KUWAHARA , ATSUSHI KOBORI , YOSHIHIDE TAKAHASHI , ASUMI TAKEI
DOI: 10.1111/J.1540-8167.2010.01812.X
关键词: Medicine 、 Catheter ablation 、 Internal medicine 、 Sinus rhythm 、 Pulmonary vein 、 valvular heart disease 、 Heart disease 、 Atrial fibrillation 、 Atrial tachycardia 、 Ablation 、 Cardiology 、 Surgery
摘要: AF Ablation in Patients With Valvular Heart Disease. Background: The purpose of this study is to evaluate the efficacy atrial fibrillation (AF) ablation patients with moderate valvular heart disease (VHD). Methods: In total, 534 consecutive who underwent were enrolled. a history valve surgery or other structural excluded. clinically VHD (group-1, n = 45) compared those without (control group-2, 436). Ipsilateral pulmonary vein antrum isolation (PVAI) was performed double Lasso technique all patients. Left (LA) linear undertaken persistent patients, if inducible after PVAI. Results: group-1 significantly older and had larger LA. PVAI successfully achieved received LA more frequently during index procedure. After median 26 months from procedure, freedom lower than group-2 off antiarrhythmic drugs (AADs) (47% vs 69%, P 0.002). Although there number total procedures at 24 last procedure (78% 87%, 0.038). There no significant difference on AADs (91% 95%, 0.356) complication rate between 2 groups. Atrial tachycardia following observed (P 0.001). Conclusion: undergoing are less likely remain sinus rhythm long term VHD. (J Cardiovasc Electrophysiol, Vol. 21, pp. 1193-1198, November 2010)