Protective effect of rutin on LPS-induced acute lung injury via down-regulation of MIP-2 expression and MMP-9 activation through inhibition of Akt phosphorylation.

作者: Wen-Ying Chen , Yi-Chun Huang , Ming-Ling Yang , Chien-Ying Lee , Chun-Jung Chen

DOI: 10.1016/J.INTIMP.2014.07.026

关键词: ImmunologyChemistryRutinLipopolysaccharidePharmacologyMacrophage inflammatory proteinPhosphorylationDownregulation and upregulationLung injuryProtein kinase BMatrix metalloproteinase

摘要: … between DEX at 1 mg kg − 1 and rutin at 100 μmol kg − 1 . ALI has been treated by DEX via … Clinically, long-term use of dexamethasone can cause serious advisor effect such as …

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