Correlation between low-level expression of the tumor suppressor gene TAp73 and the chemoresistance of human glioma stem cells.

作者: Xiaogang Hu , Nan Wu , Peiyuan Xia , Sicang Yu , Fengjun Sun

DOI: 10.1007/S00280-012-1823-0

关键词: Tumor Protein p73Cancer researchOncologyCisplatinBiologyTumor suppressor geneStem cellFlow cytometryApoptosisInternal medicineNuclear proteinGlioma

摘要: Objective Glioma stem cells (GSCs) are regarded as the root of glioma growth and recurrence. Chemoresistance is one characteristics GSCs that increases difficulties in eradicating by anticancer drugs.

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