Synergistic Activation of Inflammatory Cytokine Genes by Interferon-γ-Induced Chromatin Remodeling and Toll-like Receptor Signaling

作者: Yu Qiao , Eugenia G. Giannopoulou , Chun Hin Chan , Sung-ho Park , Shiaoching Gong

DOI: 10.1016/J.IMMUNI.2013.08.009

关键词: EnhancerSTAT1Transcription factorRNA polymerase IIEnhancer RNAsChromatin remodelingTranscription coregulatorPromoterBiologyCancer research

摘要: … TNF, IL6, and IL12B (encodes p40) gene expression is strongly induced by microbial products that are sensed by Toll-like receptors (TLRs) and other pattern recognition receptors and …

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