作者: J. E. Weatherhead , P. J. Hotez
DOI: 10.1542/PIR.36-8-341
关键词: Medicine 、 Pediatrics 、 Hepatitis 、 Ascariasis 、 Cysticercosis 、 Toxocariasis 、 Schistosomiasis 、 Malnutrition 、 Immunology 、 Trichuriasis 、 Hookworm infection
摘要: • On the basis of research evidence, worm infections are important global child health conditions causing chronic disability that lasts from childhood into adulthood (Table 1). (2)(3) Evidence Quality: B major found in developing countries include ascariasis, trichuriasis, hookworm infection, and schistosomiasis; toxocariasis, enterobiasis, cysticercosis also poor regions North America Europe. (4)(9)(13) expert consensus, children adolescents often vulnerable to acquiring large numbers worms, ie, high-intensity (Fig 1)(21)(22)(23) D consensus moderate heavy burdens cause increased morbidity because growth intellectual stunting adolescents. Many these effects may result helminth-induced malnutrition. (21)(22)(23) C commonly associated with eosinophilia. (48) (49) evidence as well helminthes can inflammation lung (asthma), gastrointestinal tract (enteritis colitis), liver (hepatitis fibrosis), urogenital tract. (7)(21)(22)(23)(27)(28)(40)(41)(43) microscopy techniques for diagnosis exhibit suboptimal sensitivities specificities, necessitating new or improved diagnostic modalities such polymerase chain reaction. (54)(55) A mass drug administration (“preventive chemotherapy”) has becomea standard practice ministries low- middle-income control intestinal helminth schistosomiasis. (67)(68) B.