SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction
作者： Fei Wang , Margaret Nguyen , F. Xiao-Feng Qin , Qiang Tong
DOI: 10.1111/J.1474-9726.2007.00304.X
关键词: Histone 、 Reactive oxygen species 、 SIRT2 、 Regulation of gene expression 、 Oxidative stress 、 Transcription factor 、 Biology 、 Sirtuin 、 NAD+ kinase 、 Biochemistry
摘要: … We report here that the expression of SIRT2 is elevated in the white adipose tissue and kidney of caloric-… Consistent with our findings, the up-regulation of FOXO activity by MST1 kinase …
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