Interaction between widening of diameter of abdominal aorta and cardiovascular risk factors and atherosclerosis burden

摘要: The aim of this study was to investigate influence traditional cardiovascular risk factors (CVRF) and subclinical atherosclerosis (ATS) burden on early stages abdominal aortic diameter (AAD) widening among adults. 2,052 consecutive patients (P) (39 % women), mean age 52 ± 13 years, were prospectively screened for CVRF, ATS, AAD. B-mode ultrasound used evaluate the largest AAD detect carotid femoral atherosclerotic plaques. Mean 15.2 ± 2.8 mm. Atherosclerotic plaques detected in 71 % patients. Significant univariate correlation between AAD, ABS found. However, multiple regression analysis showed that only seven them significantly weakly correlated with (R² = 0.27, p < 0.001). On other hand, a multivariate logistic CVRF impact enlarged AAD ≥25 mm (EAAD) as compared those AAD <25 mm. These did not account more than 30 % interaction (R² = 0.30, p = 0.001). Furthermore, despite large proportion high number rate low (1 %) scattered regardless their CHD score or ATS burden. In conclusion, these results suggest although some presence are associated EAAD, determinants still need be identified better understanding aneurysm pathogenesis.