Symmetrical neurofibroma with Schwann cell predominance and focal formation of microneurinomas.

作者: R. Schober , G. Reifenberger , G. Kremer , H. Urich

DOI: 10.1007/BF00227773

关键词: ImmunohistochemistryElectron microscopePathologyLesionSchwann cellCell growthNeurofibromaNeurofibromatosisBiologyGrowth factor

摘要: A case of symmetrical neurofibroma with onion bulbs in various stages development and progression to microneurinomas is presented. Immunohistochemistry differentiation growth factor markers as well electron microscopy showed a Schwann cell origin the concentrically arranged cells. The differed from those hypertrophic neuropathy by their more compact structure. partial expression cellular proliferation was consistent multifocal proliferative activity, confirming neoplastic nature lesion.

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