Severe dietary lysine restriction affects growth and body composition and hepatic gene expression for nitrogen metabolism in growing rats

作者: J. Kim , K. S. Lee , D.-H. Kwon , J. J. Bong , J. Y. Jeong

DOI: 10.1111/JPN.12061

关键词: Gene expressionBiochemistryNitrogen cycleComposition (visual arts)Internal medicineArginaseLysineMessenger RNAIntramuscular fatFood intakeEndocrinologyBiology

摘要: Summary Dietary lysine restriction may differentially affect body growth and lipid nitrogen metabolism, depending on the degree of restriction. This study was conducted to examine effect dietary metabolism with two different Isocaloric amino acid–defined diets containing 1.4% (adequate), 0.70% (50% moderate restriction) 0.35% (75% severe were fed from age 52 77 days for 25 days in male Sprague–Dawley rats. The 75% increased (p   0.05) metabolism. Our results demonstrate that has detrimental effects deregulate

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