Models of neurogenic inflammation as it relates to migraine

作者: Uwe Reuter , Guy Arnold

DOI: 10.1007/978-3-0348-8131-9_5

关键词: VasoconstrictionVasodilationMedicineInternal medicineMigraineAuraNeurogenic inflammationCardiologyIschemiaCortical spreading depressionVascular Disorder

摘要: For more than half a century, migraine was believed to be vascular disorder with the aura attributed cerebral vasoconstriction and ischemia headache dilation inflammation of extracranial arteries. However, there is mounting evidence that cortical spreading depression mechanism underlying (neurogenic) important vasodilation in headache. This chapter focuses on experimental models related putative mechanisms neurogenic (Tab. 1).

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