A cutaneous interstitial granulomatous dermatitis-like eruption arising in myelodysplasia with leukemic progression

摘要: Cutaneous manifestations associated with myelodysplastic syndromes (MDS) are uncommon and can occur as specific or nonspecific lesions. Recognizing these cutaneous is important they precede blood bone marrow transformation to leukemia. Granulomatous reactions have rarely been described lesions of MDS. These rare cases histologically resembled granuloma annulare, sarcoid, a generalized dermal interstitial granulomatous dermatitis (IGD) which were not leukemic infiltration. The authors report an interesting case IGD-like eruption evolving over the course MDS eventual progression systemic IGD inflammatory reaction that refers varied spectrum histologic patterns variety illnesses hypersensitivity reactions, including lymphoma In patients MDS, surveillance for leukemia critical component their follow-up care. Normally, this occurs through serial peripheral smears studies. eruptions pattern may serve additional clinical indicator in Although primarily reactive pattern, entity harbor blasts.