Estimation of Protein Requirements According to Nitrogen Balance for Older Hospitalized Adults with Pressure Ulcers According to Wound Severity in Japan

作者: Shinji Iizaka , Junko Matsuo , Chizuko Konya , Rie Sekine , Junko Sugama

DOI: 10.1111/J.1532-5415.2012.04202.X

关键词: UrineProtein requirementCreatinineSurgeryNitrogen balanceConfidence intervalAnimal scienceExudateExcretionFecesMedicine

摘要: Objectives: To estimate protein requirements in older hospitalized adults with pressure ulcers (PrU) according to systemic conditions and wound severity. Design: Secondary nitrogen balance study over 3 days. Setting: Long-term care facility. Participants: Twenty-eight PrU using a urinary catheter. Measurements: Nitrogen days was evaluated from habitual intake measured food weighing record excretion urine, feces exudate. required maintain equilibrium estimated as an average requirement linear mixed model. Results: at 0.151 gN/kg per day (95% confidence interval = 0.127�0.175 day) for all participants. The amount of loss exudate contributed little total excretion. A Charlson comorbidity index 4 or greater (the median value) related lower (P .005). Severe heavy amounts areas 7.9 cm2 were higher individuals less (both P .04). Larger area (correlation coefficient (r) 0.55, .003) heavier volume (r 0.53, .004) associated muscle hypercatabolism 3-methylhistidine/creatinine ratio. Conclusion: is 0.95 g/kg Japanese PrU, but depend on individual's condition severity range 0.75 1.30 day. can require intakes because rather than direct

参考文章(39)
Matthias J. Kaiser, Jürgen M. Bauer, Christiane Rämsch, Wolfgang Uter, Yves Guigoz, Tommy Cederholm, David R. Thomas, Patricia S. Anthony, Karen E. Charlton, Marcello Maggio, Alan C. Tsai, Bruno Vellas, Cornel C. Sieber, , Frequency of malnutrition in older adults:a multinational perspective using the Mini Nutritional Assessment Journal of the American Geriatrics Society. ,vol. 58, pp. 1734- 1738 ,(2010) , 10.1111/J.1532-5415.2010.03016.X
Hiromi Sanada, Shinji Iizaka, Yuko Matsui, Masutaka Furue, Takao Tachibana, Takeo Nakayama, Junko Sugama, Katsunori Furuta, Masahiro Tachi, Keiko Tokunaga, Yoshiki Miyachi, Scientific Education Committee of the Japanese Society of Pressure Ulcers, Clinical wound assessment using DESIGN-R total score can predict pressure ulcer healing: Pooled analysis from two multicenter cohort studies Wound Repair and Regeneration. ,vol. 19, pp. 559- 567 ,(2011) , 10.1111/J.1524-475X.2011.00719.X
Cathy Gaillard, Emmanuel Alix, Yves Boirie, Gilles Berrut, Patrick Ritz, Are elderly hospitalized patients getting enough protein Journal of the American Geriatrics Society. ,vol. 56, pp. 1045- 1049 ,(2008) , 10.1111/J.1532-5415.2008.01721.X
S Collins, M Myatt, B Golden, Dietary treatment of severe malnutrition in adults. The American Journal of Clinical Nutrition. ,vol. 68, pp. 193- 199 ,(1998) , 10.1093/AJCN/68.1.193
William M Rand, Peter L Pellett, Vernon R Young, Meta-analysis of nitrogen balance studies for estimating protein requirements in healthy adults The American Journal of Clinical Nutrition. ,vol. 77, pp. 109- 127 ,(2003) , 10.1093/AJCN/77.1.109
Erica PA Rutten, Frits ME Franssen, Marielle PKJ Engelen, Emiel FM Wouters, Nicolaas EP Deutz, Annemie MWJ Schols, Greater whole-body myofibrillar protein breakdown in cachectic patients with chronic obstructive pulmonary disease The American Journal of Clinical Nutrition. ,vol. 83, pp. 829- 834 ,(2006) , 10.1093/AJCN/83.4.829
Takehiko Ohura, Toshio Nakajo, Shingo Okada, Kenji Omura, Kayoko Adachi, Evaluation of effects of nutrition intervention on healing of pressure ulcers and nutritional states (randomized controlled trial) Wound Repair and Regeneration. ,vol. 19, pp. 330- 336 ,(2011) , 10.1111/J.1524-475X.2011.00691.X
S. Iizaka, H. Sanada, G. Nakagami, H. Koyanagi, C. Konya, J. Sugama, Quantitative estimation of exudate volume for full-thickness pressure ulcers: the ESTimation method Journal of Wound Care. ,vol. 20, pp. 453- 463 ,(2011) , 10.12968/JOWC.2011.20.10.453
Rebecca J. Stratton, Anna-Christina Ek, Meike Engfer, Zena Moore, Paul Rigby, Robert Wolfe, Marinos Elia, Enteral nutritional support in prevention and treatment of pressure ulcers: a systematic review and meta-analysis. Ageing Research Reviews. ,vol. 4, pp. 422- 450 ,(2005) , 10.1016/J.ARR.2005.03.005