Evidence-Based Recommendations for Optimal Dietary Protein Intake in Older People: A Position Paper From the PROT-AGE Study Group

摘要: New evidence shows that older adults need more dietary protein than do younger to support good health, promote recovery from illness, and maintain functionality. Older people make up for age-related changes in metabolism, such as high splanchnic extraction declining anabolic responses ingested protein. They also offset inflammatory catabolic conditions associated with chronic acute diseases occur commonly aging. With the goal of developing updated, evidence-based recommendations optimal intake by people, European Union Geriatric Medicine Society (EUGMS), cooperation other scientific organizations, appointed an international study group review needs aging (PROT-AGE Study Group). To help (>65 years) regain lean body mass function, PROT-AGE recommends average daily at least range 1.0 1.2 g per kilogram weight day. Both endurance- resistance-type exercises are recommended individualized levels safe tolerated, higher (ie, ≥ g/kg weight/d) is advised those who exercising otherwise active. Most have or even 1.2-1.5 weight/d). severe kidney disease estimated GFR <30 mL/min/1.73 m(2)), but not on dialysis, exception this rule; these individuals may limit intake. Protein quality, timing ingestion, nutritional supplements be relevant, yet sufficient specific recommendations. vulnerable losses physical function capacity, predict loss independence, falls, mortality. Thus, future studies aimed pinpointing populations include measures function.