Protein intake: effects on bone mineral density and the rate of bone loss in elderly women

作者: Prema B Rapuri , J Christopher Gallagher , Vera Haynatzka

DOI: 10.1093/AJCN/77.6.1517

关键词:

摘要: Background: The role of dietary protein in bone metabolism is controversial. Objective: We investigated the associations intake with baseline mineral density (BMD) and rate loss over 3 y postmenopausal elderly women. Design: Women aged 65‐77 (n = 489) were enrolled an osteoporosis intervention trial. studied as a percentage energy BMD 96 women placebo group 96). also examined effect interaction calcium on BMD. Results: In cross-sectional study, higher was associated significantly (P 408 mg/d. There no significant hip longitudinal study group, there association between loss. Conclusions: highest quartile (x : 72 g/d) at only when exceeded seen loss, perhaps because sample size too small or follow-up period not long enough to detect changes. Am J Clin Nutr 2003;77:1517‐25.

参考文章(59)
Zemel Mb, Linkswiler Hm, Hegsted M, Schuette S, Protein-induced hypercalciuria. Federation proceedings. ,vol. 40, pp. 2429- ,(1981)
H.C. Sherman, A.R. Rose, M.S. Rose, CALCIUM REQUIREMENT OF MAINTENANCE IN MAN Journal of Biological Chemistry. ,vol. 44, pp. 21- 27 ,(1920) , 10.1016/S0021-9258(18)86268-8
Jane E. Kerstetter, Lindsay H. Allen, Protein Intake and Calcium Homeostasis Advances in Nutritional Research. ,vol. 9, pp. 167- 181 ,(1994) , 10.1007/978-1-4757-9092-4_10
Robert P. Heaney, Robert R. Recker, Effects of nitrogen, phosphorus, and caffeine on calcium balance in women. Journal of Laboratory and Clinical Medicine. ,vol. 99, pp. 46- 55 ,(1982)
J Lutz, H M Linkswiler, Calcium metabolism in postmenopausal and osteoporotic women consuming two levels of dietary protein The American Journal of Clinical Nutrition. ,vol. 34, pp. 2178- 2186 ,(1981) , 10.1093/AJCN/34.10.2178
Sally A. Schuette, Michael B. Zemel, Hellen M. Linkswiler, Studies on the Mechanism of Protein-Induced Hypercalciuria in Older Men and Women Journal of Nutrition. ,vol. 110, pp. 305- 315 ,(1980) , 10.1093/JN/110.2.305
J E Kerstetter, K O O’Brien, K L Insogna, Dietary protein affects intestinal calcium absorption. The American Journal of Clinical Nutrition. ,vol. 68, pp. 859- 865 ,(1998) , 10.1093/AJCN/68.4.859
Ronald G Munger, James R Cerhan, Brian C-H Chiu, Prospective study of dietary protein intake and risk of hip fracture in postmenopausal women The American Journal of Clinical Nutrition. ,vol. 69, pp. 147- 152 ,(1999) , 10.1093/AJCN/69.1.147
Sue A. Shapses, Simon P. Robins, Hasina Chowdhury, Eric I. Schwartz, Short-term changes in calcium but not protein intake alter the rate of bone resorption in healthy subjects as assessed by urinary pyridinium cross-link excretion. Journal of Nutrition. ,vol. 125, pp. 2814- 2821 ,(1995) , 10.1093/JN/125.11.2814