The Glomerulus in Acute Renal Failure

摘要: During the past 10–12 years, investigators in medical renal physiology have altered their focus from examination of normal regulatory mechanisms to part upon a variety pathophysiologic models function. One most active and initial arenas evaluation has been mechanism acute failure (ARF). Several studies, derived both this country Europe, provided an unitary hypothesis which postulated pivotal role for vasoconstriction pathogenesis (Ayer et al., 1971; Oken 1966; Henry 1968; Thiel 1967). Studies supported concept that major reductions blood flow (RBF) plasma (RPF) occurred early initiating phase Chedru 1972; Hsu 1977; Flamenbaum 1972b; Munck, 1958; Hollenberg 1968). These findings led view commonly logically held at time was “vasomotor nephropathy.”