作者: Warren L. Grayson , Gordana Vunjak-Novakovic , Bojana Obradovic
DOI: 10.1007/978-3-642-21913-9_11
关键词: Biochemical engineering 、 Bioreactor 、 Engineering 、 Tissue engineering
摘要: The underlying philosophy guiding the design and development of advanced bioreactors for tissue engineering purposes is to provide environmental conditions that enable metabolically active cells in threedimensional (3D) spatial arrangements reconstruct functional tissues1. This requires receive adequate supplies nutrients maintain their viability, along with ‘relevant’ biological, physiological mechanical signals guide differentiation a chosen lineagepathway.