Effect of aerosolized colistin on multidrug-resistant Pseudomonas aeruginosa in bronchial secretions of patients without cystic fibrosis

摘要: We performed a limited microbiological study to examine the effect of aerosolized colistin (1 million international units every 8 hours) on colonization respiratory tract with Pseudomonas aeruginosa five intubated, mechanically ventilated patients in Intensive Care Unit (ICU). No adverse or side effects administered were reported. The microbial counts prior use colistin, as well during second, fourth, sixth, and eighth day after drug measured. results this preliminary suggest that was effective reducing quickly eliminating growth by sixth all studied patients.