Histomorphometric evaluation of extraction sockets and deficient alveolar ridges treated with allograft and barrier membrane: a pilot study.

作者: Hyman Smukler , Reza Setayesh , Luca Landi

DOI:

关键词: Bone allograftBarrier membraneChemistryDentistryExtraction (chemistry)Trabecular bonePolytetrafluoroethyleneBone regenerationAlveolar Ridge AugmentationDental alveolus

摘要: The aim of the study was to determine fate demineralized freeze-dried bone allograft (DFDBA) used in conjunction with a barrier membrane management extraction sockets and deficient alveolar ridges, compare amount formed that found untreated sites. Ten biopsies were obtained from 8 grafted patients. Five harvested sites during routine implant placement analyzed for comparison. In socket procedure, DFDBA packed tightly into covered an expanded polytetrafluoroethylene (e-PTFE) membrane. Primary closure achieved all cases. ridge regeneration cortical columns placed projecting outward approximately 3 mm create maintain space particles between them; then by e-PTFE Healing time ranged 23 months. At placement, cores (7 x 2 mm) harvested, fixed 10% formalin solution, prepared histologic examination. light microscopic level, no inflammation or fibrous encapsulation observed. New formation on around widespread. Histomorphometric analysis specimens carried out using trabecular volume (TBV) index. TBV maxillary test 55.03%, as compared 57.33% control cores. Unaltered made up 8.7% specimens. mandibular biopsies, 56.6%, while controls it 40.9%. still present 2.45%. results tended indicate treatment cell occlusive membranes will result new formation, predominantly process conduction, which appears be similar nature healed nonfunctional edentulous areas.

参考文章(34)
P V Goldberg, M J Werbitt, The immediate implant: bone preservation and bone regeneration. International Journal of Periodontics & Restorative Dentistry. ,vol. 12, pp. 206- 217 ,(1992)
Lekholm U, Becker Be, Higuchi K, Becker W, Schenk R, Variations in bone regeneration adjacent to implants augmented with barrier membranes alone or with demineralized freeze-dried bone or autologous grafts: a study in dogs. International Journal of Oral & Maxillofacial Implants. ,vol. 10, pp. 143- 154 ,(1995)
U Bragger, D Buser, N P Lang, S Nyman, Bone regeneration adjacent to titanium dental implants using guided tissue regeneration: a report of two cases. International Journal of Oral & Maxillofacial Implants. ,vol. 5, pp. 9- 14 ,(1990)
Min Zhang, Ralph M. Powers, Lloyd Wolfinbarger, A Quantitative Assessment of Osteoinductivity of Human Demineralized Bone Matrix Journal of Periodontology. ,vol. 68, pp. 1076- 1084 ,(1997) , 10.1902/JOP.1997.68.11.1076
D. Buser, U. Brägger, N. P. Lang, S. Nyman, Regeneration and enlargement of jaw bone using guided tissue regeneration Clinical Oral Implants Research. ,vol. 1, pp. 22- 32 ,(1990) , 10.1034/J.1600-0501.1990.010104.X
Min Zhang, Ralph M. Powers, Lloyd Wolfinbarger, Effect(s) of the Demineralization Process on the Osteoinductivity of Demineralized Bone Matrix Journal of Periodontology. ,vol. 68, pp. 1085- 1092 ,(1997) , 10.1902/JOP.1997.68.11.1085
Z. Schwartz, J.T. Mellonig, D.L. Carnes, J. De La Fontaine, D.L. Cochran, D.D. Dean, B.D. Boyan, Ability of Commercial Demineralized Freeze-Dried Bone Allograft to Induce New Bone Formation Journal of Periodontology. ,vol. 67, pp. 918- 926 ,(1996) , 10.1902/JOP.1996.67.9.918
William Becker, Burton E. Becker, Raul Caffesse, A Comparison of Demineralized Freeze‐Dried Bone and Autologous Bone to Induce Bone Formation in Human Extraction Sockets Journal of Periodontology. ,vol. 65, pp. 1128- 1133 ,(1994) , 10.1902/JOP.1994.65.12.1128
Norbert Kübler, Jürgen Reuther, Thomas Kirchner, Bernd Priessnitz, Walter Sebald, Osteoinductive, morphologic, and biomechanical properties of autolyzed, antigen-extracted, allogeneic human bone** Journal of Oral and Maxillofacial Surgery. ,vol. 51, pp. 1346- 1357 ,(1993) , 10.1016/S0278-2391(10)80141-7
Trisi P, Piattelli A, Dahlin C, Simion M, Qualitative and quantitative comparative study on different filling materials used in bone tissue regeneration: a controlled clinical study. International Journal of Periodontics & Restorative Dentistry. ,vol. 14, pp. 198- 215 ,(1994)