The 14C, 13C and 15N syntheses of MON 37500, a sulfonylurea wheat herbicide
作者： Brad D. Maxwell , Olivier G. Boyé , Kazunari Ohta
DOI: 10.1002/JLCR.934
关键词: Sulfonylurea 、 Chemistry 、 Chemical synthesis 、 Pyrimidine 、 Stereochemistry 、 Imidazopyridine 、 Yield (chemistry) 、 Ammonium chloride 、 Chloroacetic acid 、 Diethyl malonate
摘要: [14C] and [13C]MON 37500 labeled in the imidazopyridine (Im) ring system were synthesized seven steps an overall yield of 39 28%, respectively, from [2-14C] [2-13C]chloroacetic acid. [14C]MON pyrimidine (Pd) was [2-14C]diethyl malonate four 48% yield. Lastly, [15N]MON prepared three 28% [15N]ammonium chloride. Copyright © 2005 John Wiley & Sons, Ltd.
sci-hub.se 参考文章(3)
John P. Paolini, Roland K. Robins, Aromaticity in heterocyclic systems III. The structure and proton magnetic resonance spectra of certain imidazo[1,2-a]pyridines Journal of Heterocyclic Chemistry. ,vol. 2, pp. 53- 62 ,(1965) , 10.1002/JHET.5570020110
Thomas B. Ray, Sulfonylurea herbicides as inhibitors of amino acid biosynthesis in plants Trends in Biochemical Sciences. ,vol. 11, pp. 180- 183 ,(1986) , 10.1016/0968-0004(86)90137-4
Yasuo ISHIDA, Kazunari OHTA, Shigeyuki ITOH, Tatsuo NAKAHAMA, Hideki MIKI, Harutoshi YOSHIKAWA, イミダゾ [1,2-a] ピリジン部分を有する除草活性化合物新規スルホニル尿素の合成 Journal of Pesticide Science. ,vol. 18, pp. 175- 182 ,(1993) , 10.1584/JPESTICS.18.2_175