Prospective evaluation of prostate cancer detected on biopsies 1, 2, 3 and 4: when should we stop?

作者: BOB DJAVAN , VINCENT RAVERY , ALEX ZLOTTA , PIOTR DOBRONSKI , MICHAEL DOBROVITS

DOI: 10.1016/S0022-5347(05)65652-2

关键词: Prostate biopsyProspective cohort studyBiopsyProstate cancerProstatectomySurgeryUrologyProstate-specific antigenMedicineProstateCancer

摘要: Purpose: We evaluated biochemical parameters and pathological features, as well biopsy related morbidity of prostate cancer detected on biopsies 2, 3 4 in men with total serum specific antigen (PSA) between 10 ng./ml. These features were compared to those 1.Materials Methods: In this prospective European Prostate Cancer Detection study 1,051 PSA underwent transrectal ultrasound guided sextant 2 additional transition zone biopsies. All patients whom samples negative for after 6 weeks. If also negative, even performed at 8-week intervals. Those clinically localized radical prostatectomy. Pathological clinical diagnosed either 1 or organ confined disease who agreed undergo prostatectomy compared.Results: detection rate...

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