Effects of a Multicomponent Herbal Extract on the Course of Subclinical Ketosis in Dairy Cows – a Blinded Placebo-controlled Field-study

摘要: A blinded placebo-controlled multi-center on-farm trial was conducted in dairy cows with subclinical ketosis to investigate effects of a multicomponent herbal extract. Blood ketone levels were measured weekly early lactating from 16 Swiss herds. Cows subclassified based on their initial blood-β-hydroxybutyrate (≥ 1.0 [KET-low, 84 cows] and > 1.2 mmol/L [KET-high, 39 cows]) randomly distributed 3 groups treated orally extract containing Camellia sinensis, Cichcorium intybus, Gentiana lutea, Glycyrrhiza glabra, Taraxacum officinale, Trigonella foenum-graecum, Zingiber sodium propionate, or placebo twice day for 5 days. Milk yield, milk acetone, blood-β-hydroxybutyrate, glucose, nonesterified fatty acids, gamma-glutamyl transferase, glutamate dehydrogenase analyzed over 2 wk. Linear mixed effect models used data analysis. No found nonesterifed fatty acids, glucose. Significantly higher (29.71 U/L) values extract-treated animals compared propionate 7 (22.33 U/L). By trend, (1.36 mmol/L) the group KET-high-cows 14 (0.91 mmol/L). yields all treatment increased. Milking time showed significant interaction acetone: led an immediate decrease, whereas extracts resulted acetone decrease on, reaching significantly lower (3.17 mg/L) when (4.89 mg/L). In conclusion, are both likely improve cows, however, by different modes action.