REGULATION OF IMMUNE RESPONSES BY TGF-β

作者: John J. Letterio , Anita B. Roberts

DOI: 10.1146/ANNUREV.IMMUNOL.16.1.137

关键词: Antigen presentationCytokineCell biologyParacrine signallingImmune systemDendritic cellLymphokineTransforming growth factor betaCCL18BiologyImmunologyImmunology and Allergy

摘要: … of TGF-β1 mRNA in normal human peripheral blood B cells and stimulates … B-lymphoma cell lines to secrete large amounts of active TGF-β1 (63, 64). Given that TGF-β typically inhibits B …

参考文章(129)
Ling Zhu, Guillermo A Herrera, Joanne E Murphy-Ullrich, Zhi-Qiang Huang, Paul W Sanders, None, Pathogenesis of glomerulosclerosis in light chain deposition disease. Role for transforming growth factor-beta. American Journal of Pathology. ,vol. 147, pp. 375- 385 ,(1995)
Robert Flaumenhaft, Soichi Kojima, Mayumi Abe, Daniel B. Rifkin, Activation of Latent Transforming Growth Factor ß Advances in pharmacology. ,vol. 24, pp. 51- 76 ,(1993) , 10.1016/S1054-3589(08)60933-3
D B Rifkin, R L Shapiro, I Nunes, Characterization of latent TGF-beta activation by murine peritoneal macrophages. Journal of Immunology. ,vol. 155, pp. 1450- 1459 ,(1995)
E B Smeland, J Lømo, T Stokke, K Beiske, H K Blomhoff, TGF-beta 1 and cyclic AMP promote apoptosis in resting human B lymphocytes. Journal of Immunology. ,vol. 154, pp. 1634- 1643 ,(1995)
G R Welch, H L Wong, S M Wahl, Selective induction of Fc gamma RIII on human monocytes by transforming growth factor-beta. Journal of Immunology. ,vol. 144, pp. 3444- 3448 ,(1990)
K Fan, Q Ruan, L Sensenbrenner, B Chen, Transforming growth factor-beta 1 bifunctionally regulates murine macrophage proliferation Blood. ,vol. 79, pp. 1679- 1685 ,(1992) , 10.1182/BLOOD.V79.7.1679.1679
B Vandekerckhove, M De Smedt, J Plum, G Leclercq, Influence of TGF-beta on murine thymocyte development in fetal thymus organ culture. Journal of Immunology. ,vol. 154, pp. 5789- 5798 ,(1995)