Effect of charge patterns along a solid-state nanopore on polyelectrolyte translocation

摘要: We investigate the effectiveness of charge patterns along a nanopore on translocation dynamics flexible polyelectrolyte. perform three dimensional Langevin simulation uniformly charged polyelectrolyte translocating under uniform external electric field through solid-state nanopore. maintain total pore to be constant, while varying its distribution by placing alternate and uncharged sections different lengths length. Longest average time is observed for pattern corresponding an optimum section length, with major delay in during ejection stage. This length independent within range studied. A theory based Fokker-Planck formalism found successfully describe trends reasonable quantitative agreement.