POLYNUCLEOTIDE ENCODING A NOVEL HUMAN POTASSIUM CHANNEL ALPHA-SUBUNIT, K+alphaM1, AND VARIANTS THEREOF

作者: Chandra Ramanathan , Liana M Lee , Donald Jackson , Nathan Siemers , Jian Chen

DOI:

关键词: Screening methodRecombinant DNAPolynucleotideG alpha subunitPotassium channelBiochemistryBiologyStereochemistry

摘要: The present invention provides novel polynucleotides encoding K+alphaM1 polypeptides, fragments and homologues thereof. also the variant K+alphaM1.v1 K+alphaM1.v2, in addition to Also provided are vectors, host cells, antibodies, recombinant synthetic methods for producing said polypeptides. further relates diagnostic therapeutic applying these K+alphaM1, K+alphaM1.v1, K+alphaM1.v2 polypeptides diagnosis, treatment, and/or prevention of various diseases disorders related screening identifying agonists antagonists invention.

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