Suppression of SHIP2 contributes to tumorigenesis and proliferation of gastric cancer cells via activation of Akt

作者: Yan Ye , Yan Mei Ge , Miao Miao Xiao , Li Mei Guo , Qun Li

DOI: 10.1007/S00535-015-1101-0

关键词: Proto-oncogene tyrosine-protein kinase SrcCarcinogenesisCancer cellSignal transductionProtein kinase BDownregulation and upregulationMedicineInositolInternal medicineCancer researchEndocrinologyGastric mucosa

摘要: Background The Src homology 2-containing inositol 5-phosphatase 2 (SHIP2) is implicated in diabetes, arthrosclerosis, and cancer. However, the role of SHIP2 human gastric cancer remains unclear.

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