Ultrasound promoted greener synthesis of spiro[indole-3,5′-[1,3]oxathiolanes in water
作者： Anshu Dandia , Ruby Singh , Sumit Bhaskaran
DOI: 10.1016/J.ULTSONCH.2009.08.003
关键词: Microwave irradiation 、 Thioacetamide 、 Microwave 、 Indole test 、 Chemistry 、 Catalysis 、 Aqueous solution 、 Sonication 、 Organic chemistry
摘要: Abstract An aqueous mediated novel synthesis of substituted 2′amino-4′benzoyl-2′-methyl spiro[indole 3,5′-[1,3]oxathiolane]-2(1H)-ones (2a–f) was carried out from the reaction spiro [indole-3,2′-oxiranes] (1a–f) with thioacetamide in presence LiBr as catalyst. The under both microwaves and sonication results were also compared conventional method. In general, improvement rate yields observed when to microwave irradiation
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