Group B coxsackieviruses readily establish persistent infections in human lymphoid cell lines.

摘要: Exposing human lymphoid cell lines to uncloned or recently cloned group B coxsackieviruses results in the frequent establishment of chronically infected cultures. Persistence is maintained by a carrier culture mechanism involving virus spread through medium and replication among minority cells at any given time. These studies provide model for persistence highly cytocidal viruses.