Immunopathogenic Mechanisms in Experimental Myocarditis: Evidence for Autoimmunity to the Virus Receptor and Antigenic Mimicry between the Virus and Cardiocyte
作者： S. A. Huber , K. Simpson , A. Weller , M. Herzum
DOI: 10.1007/978-3-642-73610-0_17
关键词: Dilated cardiomyopathy 、 Pathogenesis 、 Medicine 、 Virus receptor 、 Virus 、 Fibrosis 、 Immunology 、 Virology 、 Myocarditis 、 Heart disease 、 Autoimmunity
摘要: The past 2 decades have witnessed remarkable advances in the understanding of pathogenesis myocarditis and dilated cardiomyopathy. Animal models picornavirus-induced heart disease helped to elucidate many factors involved susceptibility cardiac injury although much remains be learned. process can basically divided into three distinct phases: viral infection, inflammation, fibrosis
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