Genome Editing by CRISPR/Cas9: A Game Change in the Genetic Manipulation of Protists.
作者： Noelia Lander , Miguel A. Chiurillo , Roberto Docampo
DOI: 10.1111/JEU.12338
关键词: Adaptation 、 Protist 、 Cas9 、 Biology 、 CRISPR 、 Genetics 、 Organism 、 Gene 、 Genome editing 、 Model organism
摘要: … was the use of CRISPR/Cas9 to downregulate the expression of a gene family of 65 members … This work shows strong evidence of CRISPR/Cas9-mediated gene knockout in L. major. …
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