Quantitation of immunoglobulin mu-gamma 1 heavy chain switch region recombination by a digestion-circularization polymerase chain reaction method.

作者: C. C. Chu , W. E. Paul , E. E. Max

DOI: 10.1073/PNAS.89.15.6978

关键词: IsotypeRestriction siteRestriction fragmentPolymerase chain reactionRestriction enzymeImmunoglobulin Switch RegionMolecular biologyImmunoglobulin class switchingBiologyGene rearrangement

摘要: … the quantitation of the frequency of immunoglobulin regions in which deletional recombination … polymerase chain reaction (DC-PCR), measures the amount of composite Sp, S'yl regions …

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