Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching
作者： Junchao Dong , Rohit A. Panchakshari , Tingting Zhang , Yu Zhang , Jiazhi Hu
DOI: 10.1038/NATURE14970
关键词:
摘要: … Long repetitive switch (S) regions precede Cμ and downstream C H s. In mature B cells, class switch recombination (CSR) generates different antibody classes by replacing Cμ with a …
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