Global detection of DNA repair outcomes induced by CRISPR-Cas9

Fei-long Meng , Jiazhi Hu , Jianhang Yin , Mengzhu Liu
bioRxiv

32
2021
2021
Mechanisms that can promote peripheral B-cell lymphoma in ATM-deficient mice.

Suprawee Tepsuporn , Jiazhi Hu , Monica Gostissa , Frederick W. Alt
Cancer immunology research 2 ( 9) 857 -866

14
2014
REV7 is required for processing AID initiated DNA lesions in activated B cells.

Dingpeng Yang , Ying Sun , Jingjing Chen , Ying Zhang
Nature Communications 11 ( 1) 2812

4
2020
Direct Visualization of RNA-DNA Primer Removal from Okazaki Fragments Provides Support for Flap Cleavage and Exonucleolytic Pathways in Eukaryotic Cells

Bochao Liu , Jiazhi Hu , Jingna Wang , Daochun Kong
Journal of Biological Chemistry 292 ( 12) 4777 -4788

27
2017
Sap1 is a replication-initiation factor essential for the assembly of pre-replicative complex in the fission yeast Schizosaccharomyces pombe

Ling Guan , Peng He , Fang Yang , Yuan Zhang
Journal of Biological Chemistry 292 ( 15) 6056 -6075

8
2017
Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases

Richard L Frock , Jiazhi Hu , Robin M Meyers , Yu-Jui Ho
Nature Biotechnology 33 ( 2) 179 -186

455
2015
CRISPR/Cas9-mediated targeted chromosome elimination

Erwei Zuo , Xiaona Huo , Xuan Yao , Xinde Hu
Genome Biology 18 ( 1) 224 -224

152
2017
Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell development

Lijuan Zhao , Richard L. Frock , Zhou Du , Jiazhi Hu
Journal of Experimental Medicine 213 ( 9) 1921 -1936

27
2016
Highly sensitive and unbiased approach for elucidating antibody repertoires.

Sherry G. Lin , Zhaoqing Ba , Zhou Du , Yu Zhang
Proceedings of the National Academy of Sciences of the United States of America 113 ( 28) 7846 -7851

35
2016
The intra-S phase checkpoint targets Dna2 to prevent stalled replication forks from reversing.

Jiazhi Hu , Lei Sun , Fenfen Shen , Yufei Chen
Cell 149 ( 6) 1221 -1232

178
2012
Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes

Jiazhi Hu , Yu Zhang , Lijuan Zhao , Richard L. Frock
Cell 163 ( 4) 947 -959

101
2015
Detecting DNA double-stranded breaks in mammalian genomes by linear amplification–mediated high-throughput genome-wide translocation sequencing

Jiazhi Hu , Robin M Meyers , Junchao Dong , Rohit A Panchakshari
Nature Protocols 11 ( 5) 853 -871

119
2016
1
2020
Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching

Junchao Dong , Rohit A. Panchakshari , Tingting Zhang , Yu Zhang
Nature 525 ( 7567) 134 -139

96
2015
Structural insight into the assembly and conformational activation of human origin recognition complex.

Jiaxuan Cheng , Ningning Li , Xiaohan Wang , Jiazhi Hu
Cell discovery 6 ( 1) 1 -13

1
2020
Optimizing genome editing strategy by primer-extension-mediated sequencing.

Jianhang Yin , Mengzhu Liu , Yang Liu , Jinchun Wu
Cell discovery 5 ( 1) 1 -11

13
2019
ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells.

Xiaojing Liu , Tingting Liu , Yafang Shang , Pengfei Dai
Cell Research 30 ( 9) 732 -744

28
2020
Improved HTGTS for CRISPR/Cas9 off-target detection.

Jianhang Yin , Mengzhu Liu , Yang Liu , Jiazhi Hu
Bio-protocol 9 ( 9)

1
2019
Safeguarding genome integrity during gene-editing therapy in a mouse model of age-related macular degeneration

Jianhang Yin , Kailun Fang , Yanxia Gao , Liqiong Ou
Nature Communications 13 ( 1) 7867

1
2022