Postsecretory metabolism of peptides
作者： Nigel W. Bunnett
DOI: 10.1164/AJRCCM/136.6_PT_2.S27
关键词: Alimentary tract 、 Enteroendocrine cell 、 Biochemistry 、 Free nerve ending 、 Biology 、 Homeostasis 、 Peptide hormone 、 Biological activity 、 Metabolism 、 Peptide
摘要: Peptide hormones and neurotransmitters play an essential role in regulation of cellular metabolism. Once released from endocrine cell or nerve ending, peptides encounter membrane-bound soluble peptidases. The peptidases inactivate form fragments with novel biologic activity. Therefore, must a major homeostatic control, but this aspect has been neglected area. This review examines the postsecretory metabolism biologically active brain alimentary tract, 2 organs which peptide is crucial importance.
sci-hub.se 参考文章(25)
M. A. Kerr, A. J. Kenny, The purification and specificity of a neutral endopeptidase from rabbit kidney brush border. Biochemical Journal. ,vol. 137, pp. 477- 488 ,(1974) , 10.1042/BJ1370477
Tess A. Stewart, John A. Weare, Ervin G. Erdös, [37] Human peptidyl dipeptidase (converting enzyme, kininase II) Methods in Enzymology. ,vol. 80, pp. 450- 460 ,(1981) , 10.1016/S0076-6879(81)80039-0
Lentzen Hans, Jochen Palenker, Localization of the thiorphan-sensitive endopeptidase, termed enkephalinase A, on glial cells FEBS Letters. ,vol. 153, pp. 93- 97 ,(1983) , 10.1016/0014-5793(83)80125-2
Jean Costentin, Adina Vlaiculescu, Pierre Chaillet, Lucien Ben Natan, Dominique Aveaux, Jean-Charles Schwartz, Dissociated effects of inhibitors of enkephalin-metabolising peptidase or naloxone on various nociceptive responses European Journal of Pharmacology. ,vol. 123, pp. 37- 44 ,(1986) , 10.1016/0014-2999(86)90684-9
J.R. McDermott, M.A. Virmani, J.D. Turner, A.M. Kidd, Peptidases involved in the catabolism of neurotensin: Inhibitor studies using superfused rat hypothalamic slices Peptides. ,vol. 7, pp. 225- 230 ,(1986) , 10.1016/0196-9781(86)90217-2
A.H. Dickenson, Enkephalins: A new approach to pain relief? Nature. ,vol. 320, pp. 681- 682 ,(1986) , 10.1038/320681A0
K.A. Zuzel, C. Rose, J.-C. Schwartz, Assessment of the role of "enkephalinase" in cholecystokinin inactivation. Neuroscience. ,vol. 15, pp. 149- 158 ,(1985) , 10.1016/0306-4522(85)90129-0
Gilles Waksman, Romaine Bouboutou, Jocelyne Devin, Richard Besselievre, Marie-Claude Fournie-Zaluski, Bernard P. Roques, Binding of the bidentate inhibitor [3H]HACBO-Gly to the rat brain neutral endopeptidase "enkephalinase". Biochemical and Biophysical Research Communications. ,vol. 131, pp. 262- 268 ,(1985) , 10.1016/0006-291X(85)91797-8
Frederic Checler, Jean-Pierre Vincent, Patrick Kitabgi, Degradation of neurotensin by rat brain synaptic membranes: involvement of a thermolysin-like metalloendopeptidase (enkephalinase), angiotensin-converting enzyme, and other unidentified peptidases. Journal of Neurochemistry. ,vol. 41, pp. 375- 384 ,(1983) , 10.1111/J.1471-4159.1983.TB04753.X
Randal A. Skidgel, Siegfried Engelbrecht, Alice R. Johnson, Ervin G. Erdös, Hydrolysis of substance p and neurotensin by converting enzyme and neutral endopeptidase Peptides. ,vol. 5, pp. 769- 776 ,(1984) , 10.1016/0196-9781(84)90020-2