Left ventricular adaptation following orthotopic heart transplantation in children: A speckle tracking echocardiographic imaging study.
作者： Rini Sahewalla , Swati Sehgal , Jennifer Blake , Sanjeev Aggarwal
DOI: 10.1111/CTR.13632
关键词: Medicine 、 Longitudinal strain 、 Heart transplantation 、 Internal medicine 、 Cardiology 、 Lv function 、 Imaging study 、 Normal group 、 Ventricle 、 Circumferential strain 、 Population
摘要: BACKGROUND Evolution of left ventricle (LV) function in the pediatric OHT population has not been well described. Our hypothesis was that, children following without any rejection, there would be progressive normalization LV size and over 2 years. METHODS evaluated using STE conventional echo parameters at five time points patients rejection first 2 years normal controls. global peak systolic longitudinal strain (LVPLS) rate, radial circumferential (LVRS LVCS), rate were analyzed. RESULTS We had twenty two with median age 1.27 years ( IQR 0.19, 5.6 years). The LVPLS (mean ± SD) abnormal post-OHT echocardiograms 1 week (-12.4 ± 3.7) 1 month (-13.9 ± 3.7) significantly improved 6 months (-15.8 ± 3.2), 1 year (-15.7 ± 3.1), (-17.8 ± 2.8). However, remained below group even (-21.3 ± 1.76). CONCLUSION In OHT, despite absence values are impaired initial months, improve progressively but remain compared healthy
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