Petroleum Ether Extract of Cissus Quadrangularis (LINN) Stimulates the Growth of Fetal Bone during Intra Uterine Developmental Period: A Morphometric Analysis
作者： Bhagath Kumar Potu , Muddanna S Rao , N Gopalan Kutty , Kumar MR Bhat , Mallikarjuna Rao Chamallamudi
DOI: 10.1590/S1807-59322008000600018
关键词: Anatomy 、 Cissus 、 Cartilage 、 Ossification 、 Petroleum ether 、 Unossified 、 Physiology 、 Cissus quadrangularis 、 Fetus 、 Bone growth 、 Biology
摘要: OBJECTIVE: The aim of the present study was to analyze effect Cissus quadrangularis plant petroleum ether extract on development long bones during intra-uterine developmental stage in rats. METHODS: Pregnant rats (n=12) were randomly assigned into either a control group (n=6) or treatment group. treated with at dose 500 mg/kg body weight from gestation day 9 until delivery. animals received an equal volume saline. Newborn pups collected both groups for alizarin red S - alcian blue staining differentiate ossified and unossified cartilage. cartilage (bone) morphometrically analyzed using Scion image software. RESULTS: Morphometric analysis revealed that percentage total length born dams significantly higher (P<0.001- -0.0001) than CONCLUSION: results suggest maternal administration pregnancy can stimulate fetal bone growth period.
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