Phytoestrogens levels determination in the cord blood from Malaysia rural and urban populations

作者: A.M. Mustafa , N.T. Malintan , S. Seelan , Z. Zhan , Z. Mohamed

DOI: 10.1016/J.TAAP.2007.03.014

关键词: Animal scienceDaidzeinPhytoestrogensCord bloodGenistinBiologyDaidzinGenisteinBlood plasmaTraditional medicineIsoflavones

摘要: This study is a result of an analysis free and conjugated phytoestrogens daidzein, genistein, daidzin, genistin coumesterol in human cord blood plasma using LCMS. Cord was collected from urban rural populations Malaysia (n = 300) to establish simple preliminary database on the levels analyzed compounds samples. The also aimed look at babies during birth as this may have profound effect developmental process. sample clean up carried out by solid-phase extraction C18 column passed through DEAE sephadex gel before mean concentrations total were daidzein (1.4 ± 2.9 ng/ml), genistein (3.7 2.8 daidzin (3.5 3.1 (19.5 4.2 ng/ml) (3.3 3.3 ng/ml). Distribution phytoestrogen found be higher samples areas compared that areas. Copyright © 2007 Elsevier Inc. All rights reserved.

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